The influence of respiratory movements upon the circulating leukocytes.

By H. H. BIn:Iu I. N, Ml)., K. H. KELLY, Ml)., F. L. ( oRDES, BA., N. [4. PETIU K1S, M.i)., II. Kss, MA. .ND E. L. SuIII , 1 3.A. R EPEATED leukod-yte cotnnuts from ear lol)e or flnsgertip blood made ins rapid successioni will fnequnenstiy sisow mam-ked differenuces at times varyinug -more thans 100 per censt. above or below the inuitial value)3 Many aunthorities have attributed these variatid)ius to errons of samplinsg, dilutions, (oulstinsg techlsic or simply accidenstal fiiudinsgs, while otlsen inivestigators4”T report .signific-anst 1)ut unsexplainued variations upons repeated observat ionss. \Vell trained persoisnsei witis mostcareful samplinug and accunnate eqinipmenut may reduce the total d-ounnstinsg enrd)r below 12 penS (-enut.’ Despite sunc-Is pne(tluttionus, iisconsistensc-ies of greatnsagnuittnde in peniplsentil leunkocyte cotnnsts (-onstinuue(l to occur.5 No consistent nsonmal patterns of os(illationi in leukoo-yte nuuml)er has Isit-herto beets eStablished aisd the changes 1e1)Ottedl Isave heens apparenit-iy random ins